Cot inhibitor-2 |
| رقم الكتالوجGC35735 |
مثبط Cot-2 هو مثبط قوي ، انتقائي وفعال عن طريق الفم (Tpl2 / MAP3K8) مع IC50 1.6 نانومترمثبط المهد -2 يثبط إنتاج TNF-α في الدم البشري الكامل المحفز بـ LPS مع IC 50 من 0.3 ميكرومتر
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 915363-56-3
Sample solution is provided at 25 µL, 10mM.
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Cot inhibitor-2 is a COT/Tpl2 inhibitor. COT/Tpl2[1]
[1]. Wu, Junjun et al Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-production in human whole blood. Bioorganic & Medicinal Chemistry Letters (2009), 19(13), 3485-3488.
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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