Glycycoumarin |
| رقم الكتالوجGC36163 |
الجلايسيكومارين هو عامل قوي مضاد للتشنجالجلايسيكومارين هو أحد أنواع الكومارين الحيوية النشطة من عرق السوس ويعرض نشاطًا مضادًا للتشنجللجليسيكومارين أيضًا تأثير كبديمكن استخدام الجليسيكومارين Glycycoumarin في البحث عن آلام البطن وأمراض الكبد
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Cas No.: 94805-82-0
Sample solution is provided at 25 µL, 10mM.
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Glycycoumarin is a major bioactive coumarin of licorice. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress-mediated JNK and GSK-3-mediated mitochondrial pathway. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase [1] [2].
[1]. Zhang E, et al. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. Sci Rep. 2016 Nov 30;6:38138. [2]. Song X, et al. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase. Oncotarget. 2016 Oct 4;7(40):65732-65743.
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