GPR120 Agonist 1 |
| رقم الكتالوجGC36183 |
GPR120 Agonist 1 هو ناهض GPR120 قوي وانتقائي ، ويمتلك تأثيرًا واعدًا مضادًا لمرض السكر وملف تعريف أمان جيد ليكون مرشحًا للتنمية
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1628448-77-0
Sample solution is provided at 25 µL, 10mM.
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GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1]. GPR120[1]
GPR120 Agonist 1 is a potent and selective GPR120 agonist. In GPR120 transfected HEK293 cells, GPR120 Agonist 1 displays good EC50 of 42 nM and 77 nM for human GPR120 and mouse GPR120 (the calcium flux assay), respectively[1].
[1]. Zhang X, et al. Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. ACS Med Chem Lett. 2017 Jul 27;8(9):947-952.
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