الصفحة الرئيسية>>Signaling Pathways>> Proteases>> Isocitrate Dehydrogenase (IDH)>>IDH1 Inhibitor 3

IDH1 Inhibitor 3

رقم الكتالوجGC36293

مثبط IDH1 3 (المركب 6f) هو مثبط نازع هيدروجيناز 1 (IDH1) متحور ، مع IC 50 من 45 نانومتر لـ IDH1R132H

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IDH1 Inhibitor 3 التركيب الكيميائي

Cas No.: 2171081-24-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1]. IC50: 45 nM (IDH1R132H)[1].

[1]. Qiangang Zheng, et al. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (2017) 5262-5266.

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