IDH1 Inhibitor 3 |
| Catalog No.GC36293 |
IDH1 억제제 3(화합물 6f)은 IDH1R132H에 대한 IC50이 45nM인 돌연변이 등시트르산 탈수소효소 1(IDH1) 억제제입니다.
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Cas No.: 2171081-24-4
Sample solution is provided at 25 µL, 10mM.
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IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1]. IC50: 45 nM (IDH1R132H)[1].
[1]. Qiangang Zheng, et al. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (2017) 5262-5266.
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