Isosinensetin (Synonyms: 6-Demethoxynobiletin) |
| رقم الكتالوجGC36345 |
يُظهر Isosinensetin ، وهو فلافون متعدد الميثوكسيلات مستخلص من pericarpium citri reticulatae viride ، تثبيطًا على P-glycoprotein (P-gp) في خلايا MDR1-MDCKII
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Cas No.: 17290-70-9
Sample solution is provided at 25 µL, 10mM.
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Isosinensetin, a polymethoxylated flavone extracted from pericarpium citri reticulatae viride, exhibits inhibition on P-glycoprotein (P-gp) in MDR1-MDCKII cells[1][2]. P-glycoprotein[2]
[1]. Wang D, et al. Identification of polymethoxylated flavones from green tangerine peel (Pericarpium Citri Reticulatae Viride) by chromatographic and spectroscopic techniques. J Pharm Biomed Anal. 2007 May 9;44(1):63-9. [2]. Bai J, et al. Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure-activity relationships. Toxicol Appl Pharmacol. 2019 Apr 15;369:49-59.
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