MF-438 |
| رقم الكتالوجGC36604 |
MF-438 هو مثبط قوي ومتوفر حيوياً لـ stearoyl-CoA desaturase 1 (SCD1) مع IC50 من 2.3 نانومتر لـ rSCD1
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 921605-87-0
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1]. EC50: 2.3 nM (rSCD1)[1]
MF-438 exhibits an ED50 between 1 and 3 mg/kg in a mouse model[1].
[1]. LÉger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *