PACAP-38 (31-38), human, mouse, rat |
رقم الكتالوجGC36841 |
PACAP-38 (31-38) ، الإنسان ، الفأر ، الجرذ هو منشط لمستقبلات PAC1 ويزيد من نشاط α-secretase
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Cas No.: 138764-85-9
Sample solution is provided at 25 µL, 10mM.
PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production[1]. PACAP is a potent activator of cAMP formation[2].
[1]. Braas KM, et al. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Ann N Y Acad Sci. 1996 Dec 26;805:204-16. [2]. Lania A, et al. Mechanism of action of pituitary adenylate cyclase-activating polypeptide (PACAP) in human nonfunctioning pituitary tumors. J Neuroendocrinol. 1995 Sep;7(9):695-702.
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