الصفحة الرئيسية>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>Teglicar

Teglicar

رقم الكتالوجGC37754

Teglicar هو شكل إسوي للكبد انتقائي وقابل للانعكاس من مثبط carnitine palmitoyl-transferase 1 (L-CPT1) بقيمة IC50 تبلغ 0.68 ميكرومتر وقيمة كي 0.36 ميكرومتر

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Teglicar التركيب الكيميائي

Cas No.: 250694-07-6

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1]. IC50: L-CPT1[1]

[1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51.

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Average Rating: 5 ★★★★★ (Based on Reviews and 26 reference(s) in Google Scholar.)

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