Teglicar |
Catalog No.GC37754 |
Teglicar est une isoforme hépatique sélective et réversible active par voie orale de l'inhibiteur de la carnitine palmitoyl-transférase 1 (L-CPT1) avec une valeur IC50 de 0,68 μM et une valeur Ki de 0,36 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 250694-07-6
Sample solution is provided at 25 µL, 10mM.
Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1]. IC50: L-CPT1[1]
[1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51.
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