Teglicar |
Katalog-Nr.GC37754 |
Teglicar ist ein selektiver und reversibler oral aktiver Hemmer der Leber-Isoform von Carnitin-Palmitoyl-Transferase 1 (L-CPT1) mit einem IC50-Wert von 0,68 μM und einem Ki-Wert von 0,36 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 250694-07-6
Sample solution is provided at 25 µL, 10mM.
Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1]. IC50: L-CPT1[1]
[1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51.
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