PTD-p65-P1 Peptide TFA |
رقم الكتالوجGC38520 |
PTD-p65-P1 Peptide TFA هو عامل نسخ نووي انتقائي فعال مثبط NF-B ويستمد من الوحدة الفرعية p65 لبقايا الأحماض الأمينية NF-κB 271-282 ، والتي تمنع بشكل انتقائي تنشيط NF-B الناجم عن التحفيز الالتهابي المختلف ، أسفل - تنظيم التعبير الجيني بوساطة NF- κB وتنظيم موت الخلايا المبرمج
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Sample solution is provided at 25 µL, 10mM.
PTD-p65-P1 Peptide TFA is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli[1].
[1]. Takada Y, et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem. 2004 Apr 9;279(15):15096-104.
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