PTD-p65-P1 Peptide TFA |
| Catalog No.GC38520 |
PTD-p65-P1 Peptide TFA es un inhibidor potente y selectivo del factor de transcripciÓn nuclear NF-κB y deriva de la subunidad p65 de los residuos de aminoÁcidos NF-κB 271-282, que inhibe selectivamente la activaciÓn de NF-κB inducida por diversos estÍmulos inflamatorios, hacia abajo -regulan la expresiÓn génica mediada por NF-κB y aumentan la apoptosis.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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PTD-p65-P1 Peptide TFA is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli[1].
[1]. Takada Y, et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem. 2004 Apr 9;279(15):15096-104.
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