GNE 0723 |
رقم الكتالوجGC31270 |
GNE 0723 هو مُعدِّل خيفي إيجابي نفاذي للدماغ من NMDAR ، مع EC50 من 21 نانومتر لـ GluN2A ، 7.4 و 6.2 ميكرومتر لـ GluN2C و GluN2D ، على التوالي.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1883518-31-7
Sample solution is provided at 25 µL, 10mM.
GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.
GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively[1].
[1]. Villemure E, et al. GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett. 2016 Oct 31;8(1):84-89.
Average Rating: 5
(Based on Reviews and 20 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *