GSK2643943A |
| رقم الكتالوجGC34354 |
GSK2643943A هو مثبط إنزيم (DUB) يستهدف USP20GSK2643943A لها تقارب مع IC50 من 160 نانومتر لـ USP20 / Ub-RhoGSK2643943A له فعالية مضادة للأورام ويمكن استخدامه للبحث عن سرطان الخلايا الحرشفية الفموي (OSCC)
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Cas No.: 2449301-27-1
Sample solution is provided at 25 µL, 10mM.
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GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC50 of 160 nM for USP20/Ub-Rho.
[1]. "Harrigan JA, et al.Deubiquitylating enzymes and drug discovery: emerging opportunities.Nat Rev Drug Discov. 2018 Jan;17(1):57-78." [2]. Nishi Kumari, et al. Targeting the Ubiquitin Proteasome System in Cancer
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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