GSK2643943A |
| Catalog No.GC34354 |
GSK2643943A는 USP20을 표적으로 하는 유비퀴틴화효소(DUB) 억제제이다. GSK2643943A는 USP20/Ub-Rho에 대해 160nM의 IC50과 친화력이 있습니다. GSK2643943A는 항종양 효능이 있어 구강 편평 세포 암종(OSCC) 연구에 사용할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2449301-27-1
Sample solution is provided at 25 µL, 10mM.
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GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC50 of 160 nM for USP20/Ub-Rho.
[1]. "Harrigan JA, et al.Deubiquitylating enzymes and drug discovery: emerging opportunities.Nat Rev Drug Discov. 2018 Jan;17(1):57-78." [2]. Nishi Kumari, et al. Targeting the Ubiquitin Proteasome System in Cancer
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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