GSK840 (Synonyms: GSK'840) |
| رقم الكتالوجGC34605 |
GSK840 (GSK'840) هو مثبط بروتين كيناز 3 (RIP3 أو RIPK3) يتفاعل مع مستقبلات ، والذي يربط مجال كيناز RIP3 مع IC50 من 0.9 نانومتر ، ويثبط نشاط كيناز مع IC 50 من 0.3 نانومتر
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Cas No.: 2361146-30-5
Sample solution is provided at 25 µL, 10mM.
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GSK840 (GSK’840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 0.9 nM, and inhibits kinase activity with an IC50 of 0.3 nM[1]. IC50: 0.3 nM (RIP3)[1]
Reference:
[1]. Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.
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