HN37 |
| رقم الكتالوجGC64806 |
HN37 كعقار مرشح قوي ومستقر كيميائيًا مضادًا للصرع ، مع EC50 من 37 نانومتر لـ KCNQ2
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Cas No.: 1821222-10-9
Sample solution is provided at 25 µL, 10mM.
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HN37 as a potent and chemically stable antiepileptic drug candidate, with an EC50 of 37 nM for KCNQ2[1].
HN37 is a potent neuronal Kv7 activator with a subtype selectivity similar to RTG[1].
[1]. Yang-Ming Zhang, et al. Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate. J Med Chem. 2021 May 13;64(9):5816-5837.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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