>>Signaling Pathways>> Membrane Transporter/Ion Channel>> Potassium Channel>>HN37

HN37

Catalog No.GC64806

HN37은 KCNQ2에 대해 37nM의 EC50을 갖는 강력하고 화학적으로 안정적인 항간질 약물 후보입니다.

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HN37 Chemical Structure

Cas No.: 1821222-10-9

Size 가격 재고 수량
5 mg
US$522.00
재고 있음
10 mg
US$882.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

HN37 as a potent and chemically stable antiepileptic drug candidate, with an EC50 of 37 nM for KCNQ2[1].

HN37 is a potent neuronal Kv7 activator with a subtype selectivity similar to RTG[1].

[1]. Yang-Ming Zhang, et al. Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate. J Med Chem. 2021 May 13;64(9):5816-5837.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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