L-689502 |
| رقم الكتالوجGC32013 |
L-689502 هو مثبط قوي للبروتياز HIV-L مع IC 50 من 1 نانومتر
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 138483-63-3
Sample solution is provided at 25 µL, 10mM.
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L-689502 is a potent inhibitor of HIV-l protease with an IC50 of 1 nM.
Both L694746 and L-689502 inhibit HIV-l ptotease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound exhibiting an IC50 of 2 μM. L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502[1].
[1]. Lingham RB, et al. HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1456-61.
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