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L-689502

Katalog-Nr.GC32013

L-689502 ist ein potenter Inhibitor der HIV-1-Protease mit einem IC50 von 1 nM.

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L-689502 Chemische Struktur

Cas No.: 138483-63-3

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Sample solution is provided at 25 µL, 10mM.

Description Protocol Chemical Properties Product Documents Related Products

L-689502 is a potent inhibitor of HIV-l protease with an IC50 of 1 nM.

Both L694746 and L-689502 inhibit HIV-l ptotease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound exhibiting an IC50 of 2 μM. L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502[1].

[1]. Lingham RB, et al. HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1456-61.

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