L-Alanyl-L-Glutamine (Synonyms: Ala-Gln, L-Ala-L-Gln) |
| رقم الكتالوجGC44029 |
يعتبر L-Alanyl-L-glutamine ، وهو عبارة عن ثنائي ببتيد الجلوتامين ، مفيدًا لنظام مضادات الأكسدة ، ويخفف الالتهاب ، وقد يعدل استجابة بروتين الصدمة الحرارية (HSP) في المواقف التقويضية
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Cas No.: 39537-23-0
Sample solution is provided at 25 µL, 10mM.
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L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.
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