MPEG-2000-DSPE (Synonyms: 1,2-DSPE-MPEG(5000), Methyl-PEG2000-DSPE, MPEG-2000-DSPE) |
| رقم الكتالوجGC64095 |
MPEG-2000-DSPE عبارة عن اتحاد فوسفوليبيد PEG ، وله قابلية للماء وقابلية للماءيستخدم MPEG-2000-DSPE في تركيب الجسيمات الشحمية ، ويزيد من قابلية الماء على سطح الجسيمات الشحمية ، وبالتالي يزيد من طول عمر الجسيمات الشحمية في الدورة الدموية لدراسة العوامل المضادة للسرطان والملاريا
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Cas No.: 147867-65-0
Sample solution is provided at 25 µL, 10mM.
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MPEG-2000-DSPE is a phospholipid PEG conjugate, has both hydrophilicity and hydrophobility. MPEG-2000-DSPE is used in the synthesis of liposomes, increases the hydrophilicity on the surface of liposomes, consequently increasing the longevity of liposomes in the blood circulation for the study of anticancer and antimalarial agents[1][2].
[1]. Rathore SS, et al. Effect of surface charge and density of distearylphosphatidylethanolamine-mPEG-2000 (DSPE-mPEG-2000) on the cytotoxicity of liposome-entrapped ricin: effect of lysosomotropic agents. Int J Pharm. 2008;350(1-2):79-94.
[2]. Hasan GM, et al. Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine-Phosphatidylcholine Liposomes. J Parasitol Res. 2011;2011:120462.
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