MPEG-2000-DSPE (Synonyms: 1,2-DSPE-MPEG(5000), Methyl-PEG2000-DSPE, MPEG-2000-DSPE) |
| カタログ番号GC64095 |
MPEG-2000-DSPE はリン脂質 PEG コンジュゲートであり、親水性と疎水性を併せ持っています。 MPEG-2000-DSPE はリポソームの合成に使用され、リポソーム表面の親水性を高め、その結果、抗がん剤および抗マラリア剤の研究のために血液循環中のリポソームの寿命を延ばします 。
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Cas No.: 147867-65-0
Sample solution is provided at 25 µL, 10mM.
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MPEG-2000-DSPE is a phospholipid PEG conjugate, has both hydrophilicity and hydrophobility. MPEG-2000-DSPE is used in the synthesis of liposomes, increases the hydrophilicity on the surface of liposomes, consequently increasing the longevity of liposomes in the blood circulation for the study of anticancer and antimalarial agents[1][2].
[1]. Rathore SS, et al. Effect of surface charge and density of distearylphosphatidylethanolamine-mPEG-2000 (DSPE-mPEG-2000) on the cytotoxicity of liposome-entrapped ricin: effect of lysosomotropic agents. Int J Pharm. 2008;350(1-2):79-94.
[2]. Hasan GM, et al. Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine-Phosphatidylcholine Liposomes. J Parasitol Res. 2011;2011:120462.
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