Nimorazole (Synonyms: Acterol, Naxofem, Naxogin, Nitrimidazine, NSC 107524) |
| رقم الكتالوجGC11113 |
Nimorazole (K-1900) ، 2-نيتروإيميدازول ، هو محسس للإشعاع الخلوي ناقص التأكسج
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6506-37-2
Sample solution is provided at 25 µL, 10mM.
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Nimorazole (K-1900) is a nitroimidazole anti-infective.
Nimorazole significantly improves the effect of radiotherapeutic management of supraglottic and pharynx tumors and can be given without major side-effects [1, 2]. Nimorazole is the only such agent to have shown a significant effect in a randomized controlled trial in head and neck cancer [3].
References:
[1]. Overgaard, J., et al., A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85. Radiother Oncol, 1998. 46(2): p. 135-46.
[2]. Roy, R.B., S.M. Laird, and L. Heasman, Treatment of trichomoniasis in the female. A comparison of metronidazole and nimorazole. Br J Vener Dis, 1975. 51(4): p. 281-4.
[3]. Henk, J.M., K. Bishop, and S.F. Shepherd, Treatment of head and neck cancer with CHART and nimorazole: phase II study. Radiother Oncol, 2003. 66(1): p. 65-70.
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