Pemigatinib (Synonyms: INCB054828) |
| رقم الكتالوجGC32915 |
Pemigatinib (INCB054828) هو مثبط فعال عن طريق الفم وانتقائي لـ FGFR مع IC50s 0.4 نانومتر ، 0.5 نانومتر ، 1.2 نانومتر ، 30 نانومتر لـ FGFR1 ، FGFR2 ، FGFR3 ، FGFR4 ، على التوالييحتوي Pemigatinib على احتمالية الإصابة بسرطان القنوات الصفراوية
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Cas No.: 1513857-77-6
Sample solution is provided at 25 µL, 10mM.
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Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.
[1]. Arudra K, et al. Calcinosis cutis dermatologic toxicity associated with fibroblast growth factor receptor inhibitor for the treatment of Wilms tumor. J Cutan Pathol. 2018 Oct;45(10):786-790.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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