OR-1896 |
| رقم الكتالوجGC39415 |
OR-1896 هو مستقلب نشط طويل العمر من Levosimendan
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 220246-81-1
Sample solution is provided at 25 µL, 10mM.
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OR-1896 is an active long-lived metabolite of Levosimendan. OR-1896 is a highly selective phosphodiesterase (PDE) III isoform inhibitor and a powerful vasodilator. OR-1896 can open ATP-sensitive K+ channels and has Ca2+-sensitizing effect. OR-1896 mitigates cardiomyocyte apoptosis, cardiac remodeling and myocardial inflammation[1].
[1]. Papp, Z, et al., Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan. Int J Cardiol. 2012 Aug 23;159(2):82-7.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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