PARP14 inhibitor H10 |
| رقم الكتالوجGC39302 |
مثبط PARP14 H10 ، المركب H 10 ، هو مثبط انتقائي ضد PARP14 (IC50 = 490 نانومتر) ، على PARPs الأخرى (≈24 أضعاف على PARP1)يحث مثبط PARP14 H10 على موت الخلايا المبرمج الخلوي caspase-3/7
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2084811-68-5
Sample solution is provided at 25 µL, 10mM.
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PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1].
[1]. Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253.
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