PARP14 inhibitor H10 |
Catalog No.GC39302 |
PARP14 억제제 H10, 화합물 H 10은 PARP14(IC50=490 nM)에 대한 선택적 억제제이며, 다른 PARP(PARP1에 비해 ≈24배)입니다. PARP14 억제제 H10은 caspase-3/7 매개 세포 사멸을 유도합니다.
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Cas No.: 2084811-68-5
Sample solution is provided at 25 µL, 10mM.
PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1].
[1]. Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253.
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