>>Signaling Pathways>> Chromatin/Epigenetics>> PARP>>PARP14 inhibitor H10

PARP14 inhibitor H10

Catalog No.GC39302

PARP14 억제제 H10, 화합물 H 10은 PARP14(IC50=490 nM)에 대한 선택적 억제제이며, 다른 PARP(PARP1에 비해 ≈24배)입니다. PARP14 억제제 H10은 caspase-3/7 매개 세포 사멸을 유도합니다.

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PARP14 inhibitor H10 Chemical Structure

Cas No.: 2084811-68-5

Size 가격 재고 수량
1mg
US$274.00
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5mg
US$881.00
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10mg
US$1,474.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1].

[1]. Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253.

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