PDD 00017238 |
رقم الكتالوجGC50638 |
PDD 00017238 هو مثبط قوي لـ Poly (ADP-ribose) Glycohydrolase (PARG) ، مع قيم EC50 تبلغ 40 نانومتر و 55 نانومتر في الفحص الكيميائي الحيوي و POM الخلية ، على التوالي.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1952247-05-0
Sample solution is provided at 25 µL, 10mM.
High affinity and potent PARG inhibitor (Kd = 3.09 nM; IC50 = 40 nM). Negative control PDD 00031705 also available.
James et al (2016) First-in-class chemical probes against poly(ADP-ribose) glycohydrolase (PARG) inhibit DNA repair with differential pharmacology to Olaparib. ACS Chem.Biol. 11 3179 PMID:27689388
Average Rating: 5
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