PDD 00017238 |
| Catalog No.GC50638 |
PDD 00017238은 폴리(ADP-리보스) 당가수분해효소(PARG)의 강력한 억제제이며, 생화학적 분석 및 세포 POM에서 각각 EC50 값이 40nM 및 55nM입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1952247-05-0
Sample solution is provided at 25 µL, 10mM.
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High affinity and potent PARG inhibitor (Kd = 3.09 nM; IC50 = 40 nM). Negative control PDD 00031705 also available.
James et al (2016) First-in-class chemical probes against poly(ADP-ribose) glycohydrolase (PARG) inhibit DNA repair with differential pharmacology to Olaparib. ACS Chem.Biol. 11 3179 PMID:27689388
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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