Pemigatinib (Synonyms: INCB054828) |
Catalog No.GC32915 |
페미가티닙(INCB054828)은 FGFR1, FGFR2, FGFR3, FGFR4에 대해 IC50이 각각 0.4nM, 0.5nM, 1.2nM, 30nM인 경구 활성 선택적 FGFR 억제제입니다. 페미가티닙은 담관암의 가능성이 있습니다.
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Cas No.: 1513857-77-6
Sample solution is provided at 25 µL, 10mM.
Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.
[1]. Arudra K, et al. Calcinosis cutis dermatologic toxicity associated with fibroblast growth factor receptor inhibitor for the treatment of Wilms tumor. J Cutan Pathol. 2018 Oct;45(10):786-790.
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