الصفحة الرئيسية>>Signaling Pathways>> Microbiology & Virology>> SARS-CoV>>PF-00835231

PF-00835231

رقم الكتالوجGC62133

PF-00835231 هو مثبط للبروتياز (3CLpro) يشبه CoV-2 cysteine 3C ، مع IC50s من 0.27 نانومتر و 4 نانومتر لـ SARS CoV-2 و SARS CoV-1 3CLpro ، على التوالي

Products are for research use only. Not for human use. We do not sell to patients.

PF-00835231 التركيب الكيميائي

Cas No.: 870153-29-0

الحجم السعر المخزون الكميّة
5 mg
153٫00
متوفر
10 mg
252٫00
متوفر
25 mg
497٫00
متوفر
50 mg
855٫00
متوفر
100 mg
1215٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 is developed for the research of anti-SARS-CoV-2/COVID-19[1].

[1]. Robert L Hoffman, et al. Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19. J Med Chem. 2020 Nov 12;63(21):12725-12747.

مراجعات

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