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PF-00835231

Katalog-Nr.GC62133

PF-00835231 ist ein Inhibitor der CoV-2-Cystein-3C-Ähnlichen Protease (3CLpro) mit IC50-Werten von 0,27 nM und 4 nM fÜr SARS CoV-2 bzw. SARS CoV-1 3CLpro.

Products are for research use only. Not for human use. We do not sell to patients.

PF-00835231 Chemische Struktur

Cas No.: 870153-29-0

Größe Preis Lagerbestand Menge
5 mg
153,00 $
Auf Lager
10 mg
252,00 $
Auf Lager
25 mg
497,00 $
Auf Lager
50 mg
855,00 $
Auf Lager
100 mg
1.215,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 is developed for the research of anti-SARS-CoV-2/COVID-19[1].

[1]. Robert L Hoffman, et al. Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19. J Med Chem. 2020 Nov 12;63(21):12725-12747.

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