Cell Cycle/Checkpoint
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.
Research Areas
- ATM/ATR(28)
- Aurora Kinase(36)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(52)
- CRM1(10)
- Cyclin-Dependent Kinases(70)
- E1 enzyme(1)
- G-quadruplex(16)
- Haspin(7)
- HMTase(1)
- Kinesin(32)
- Ksp(4)
- Microtubule/Tubulin(304)
- Mps1(17)
- Mitotic(7)
- RAD51(13)
- ROCK(76)
- Rho(13)
- PERK(22)
- PLK(51)
- PTEN(7)
- Wee1(17)
- PAK(29)
- Arp2/3 Complex(10)
- Dynamin(18)
- ECM & Adhesion Molecules(53)
- Cholesterol Metabolism(10)
- Endomembrane System & Vesicular Trafficking(34)
- G1(50)
- G2/M(35)
- G2/S(16)
- Genotoxic Stress(22)
- Inositol Phosphates(65)
- Proteolysis(179)
- Cytoskeleton & Motor Proteins(78)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(2)
- MARK(4)
- NEKs(9)
- ATF6(2)
- ClpP(6)
- Disulfidptosis(1)
- HMG Family(1)
- PDI(1)
- SWI/SNF Complex(7)
- VISTA(4)
- HOXA(1)
- Mitosis(2)
Products Related to Cell Cycle/Checkpoint(1553)
- GC49093Safflower RedCAS: 36338-96-2
Safflower red is an active substance extracted from the flowers of the safflower plant ( Carthamus tinctorius ).
- GC49108Racecadotril-d5CAS: 1246815-11-1Purity: >99.00%
An internal standard for the quantification of racecadotril
- GC49128Phenylbutazone-d9CAS: 1189479-75-1Purity: >99.00%
An internal standard for the quantification of phenylbutazone
- GC49142IsorhoifolinCAS: 552-57-8Purity: >98.00%
Isorhoifolin هو جليكوسيد الفلافونويد من أوراق periploca nigrescens
- GC49204Nefazodone-d6 (hydrochloride)CAS: 1330236-06-0Purity: >99.00%
An internal standard for the quantification of nefazodone
- GC49205L-Leu-AMC (hydrochloride)CAS: 62480-44-8Purity: >98.00%
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) هيدروكلوريد هو ركيزة ببتيدل زرقاء زاهية مفلورة لـ LAP3 (ليسين أمينوببتيداز).
- GC49293Dichlorvos-d6CAS: 203645-53-8Purity: >99.00%
An internal standard for the quantification of dichlorvos
- GC49344Fisetin-d5CAS: 2909407-29-8Purity: >99.00%
An internal standard for the quantification of fisetin
- GC493622-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxalineCAS: 77500-04-0Purity: >95.00%
A food-derived carcinogen
- GC49387Berberine-d6 (chloride)Purity: >99.00%
An internal standard for the quantification of berberine
- GC4939013C6-4-NitroanilineCAS: 1028361-70-7Purity: >98.00%
An internal standard for the quantification of 4-nitroaniline
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49089 | FR900359 | 107530-18-7 | - | |
FR900359 is an inhibitor of G proteins Gα q , Gα 11 , and Gα 14 with IC 50 values of 13.18, 10.47, and 10nM, respectively and is isolated from the leaves of the ornamental plant Ardisia crenata | ||||
| GC49093 | Safflower Red | 36338-96-2 | - | |
Safflower red is an active substance extracted from the flowers of the safflower plant ( Carthamus tinctorius ). | ||||
| GC49108 | Racecadotril-d5 | 1246815-11-1 | >99.00% | |
An internal standard for the quantification of racecadotril | ||||
| GC49124 | EN219 | 380351-29-1 | >95.00% | |
EN219 عبارة عن رابطة تساهمية تركيبية انتقائية بشكل معتدل ضد سيستين N-terminal (C8) لـ RNF114 مع IC50 من 470 نانومتر. EN219 يمنع التواجد الذاتي بوساطة RNF114 وانتشار p21. | ||||
| GC49128 | Phenylbutazone-d9 | 1189479-75-1 | >99.00% | |
An internal standard for the quantification of phenylbutazone | ||||
| GC49142 | Isorhoifolin | 552-57-8 | >98.00% | |
Isorhoifolin هو جليكوسيد الفلافونويد من أوراق periploca nigrescens | ||||
| GC49145 | Z-FR-AMC (trifluoroacetate salt) | - | >98.00% | |
A fluorogenic substrate for cathepsin L | ||||
| GC49163 | N’-Nitrosonornicotine | 80508-23-2 | >98.00% | |
An N-nitrosamine and a carcinogen | ||||
| GC49186 | O-Demethyl Apremilast | 1384441-38-6 | >95.00% | |
An active metabolite of apremilast | ||||
| GC49204 | Nefazodone-d6 (hydrochloride) | 1330236-06-0 | >99.00% | |
An internal standard for the quantification of nefazodone | ||||
| GC49205 | L-Leu-AMC (hydrochloride) | 62480-44-8 | >98.00% | |
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) هيدروكلوريد هو ركيزة ببتيدل زرقاء زاهية مفلورة لـ LAP3 (ليسين أمينوببتيداز). | ||||
| GC49244 | 4-oxo Isotretinoin | 71748-58-8 | >98.00% | |
An active metabolite of isotretinoin | ||||
| GC49280 | GSK579289A | 929095-23-8 | >98.00% | |
A Plk1 inhibitor | ||||
| GC49293 | Dichlorvos-d6 | 203645-53-8 | >99.00% | |
An internal standard for the quantification of dichlorvos | ||||
| GC49305 | H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt) | - | >95.00% | |
An RGD-containing tetrapeptide | ||||
| GC49322 | GGACK (hydrochloride) | - | >95.00% | |
A uPA and factor Xa inhibitor | ||||
| GC49334 | Chroman 1 (hydrochloride hydrate) | - | >98.00% | |
A ROCK2 inhibitor | ||||
| GC49344 | Fisetin-d5 | 2909407-29-8 | >99.00% | |
An internal standard for the quantification of fisetin | ||||
| GC49345 | Coelenterazine hcp | 123437-32-1 | >90.00% | |
Coelenterazine hcp هو نظير Coelenterazine | ||||
| GC49351 | N-Nitroso Atenolol | 134720-04-0 | >90.00% | |
A genotoxic derivative of (±)-atenolol | ||||
| GC49353 | N-Nitroso Metoprolol | 138768-62-4 | >90.00% | |
A genotoxic derivative of metoprolol | ||||
| GC49362 | 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline | 77500-04-0 | >95.00% | |
A food-derived carcinogen | ||||
| GC49387 | Berberine-d6 (chloride) | - | >99.00% | |
An internal standard for the quantification of berberine | ||||
| GC49390 | 13C6-4-Nitroaniline | 1028361-70-7 | >98.00% | |
An internal standard for the quantification of 4-nitroaniline | ||||