Cell Cycle/Checkpoint
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.
Research Areas
- ATM/ATR(28)
- Aurora Kinase(36)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(52)
- CRM1(10)
- Cyclin-Dependent Kinases(70)
- E1 enzyme(1)
- G-quadruplex(16)
- Haspin(7)
- HMTase(1)
- Kinesin(32)
- Ksp(4)
- Microtubule/Tubulin(304)
- Mps1(17)
- Mitotic(7)
- RAD51(13)
- ROCK(76)
- Rho(13)
- PERK(22)
- PLK(51)
- PTEN(7)
- Wee1(17)
- PAK(29)
- Arp2/3 Complex(10)
- Dynamin(18)
- ECM & Adhesion Molecules(53)
- Cholesterol Metabolism(10)
- Endomembrane System & Vesicular Trafficking(34)
- G1(50)
- G2/M(35)
- G2/S(16)
- Genotoxic Stress(22)
- Inositol Phosphates(65)
- Proteolysis(179)
- Cytoskeleton & Motor Proteins(78)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(2)
- MARK(4)
- NEKs(9)
- ATF6(2)
- ClpP(6)
- Disulfidptosis(1)
- HMG Family(1)
- PDI(1)
- SWI/SNF Complex(7)
- VISTA(4)
- HOXA(1)
- Mitosis(2)
Products Related to Cell Cycle/Checkpoint(1553)
- GC49393all-trans-13,14-DihydroretinolCAS: 115797-14-3Purity: >95.50%
A metabolite of all- trans retinoic acid
- GC49404Paclitaxel CCAS: 153415-45-3Purity: >95.00%
A taxoid and an inhibitor of microtubule depolymerization
- GC49412NSC 756093CAS: 1629908-92-4Purity: >98.00%
NSC 756093 هو مثبط قوي لتفاعل GBP1: PIM1. يمكن لـ NSC 756093 أن يعيد المقاومة إلى باكليتاكسيل. يمكن استخدام NSC 756093 في أبحاث سرطان المبيض.
- GC49419Aniline-d5CAS: 4165-61-1Purity: >99.00%
An internal standard for the quantification of aniline
- GC49430Wee1 InhibitorCAS: 622855-37-2Purity: >95.00%
مثبط Wee1 هو أحد مثبطات Wee1 kinase القوية مع IC50 من 0.011 μ ؛ M.
- GC494437α-hydroxy CholesterolCAS: 566-26-7Purity: >98.00%
7α-hydroxy Cholesterol هو أكسيد كولسترول ويتكون من الأكسدة الأنزيمية وغير الأنزيمية.
- GC49482(±)-Nornicotine-d4CAS: 66148-18-3Purity: >99.00%
An internal standard for the quantification of (±)-nornicotine
- GC49486Meglutol-d3CAS: 59060-36-5Purity: >99.00%
An internal standard for the quantification of meglutol
- GC49491N′-Nitrosonornicotine-d4CAS: 66148-19-4Purity: >99.00%
An internal standard for the quantification of N’-nitrosonornicotine
- GC49532S-(1,2-Dichlorovinyl)-Cysteine (hydrochloride)CAS: 2508026-62-6Purity: >95.00%
A nephrotoxin and metabolite of trichloroethylene
- GC49547L-Glutamic Acid γ-p-Nitroanilide (hydrate)CAS: 122864-94-2Purity: >95.00%
A colorimetric substrate for γ-glutamyl transpeptidase
- GC49674SchizandrinCAS: 7432-28-2Purity: >97.00%
يتم عزل شيزاندرين (شيزاندرين) ، وهو قشور ثنائي البنزين حلقي حلقي ، من ثمار شيساندرا تشينينسيس بايل.
- GC49682Dabigatran-d3CAS: 1246817-44-6Purity: >99.00%
An internal standard for the quantification of dabigatran
- GC49684Dabigatran-13C-d3CAS: 2967480-55-1Purity: >99.00%
An internal standard for the quantification of dabigatran
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49393 | all-trans-13,14-Dihydroretinol | 115797-14-3 | >95.50% | |
A metabolite of all- trans retinoic acid | ||||
| GC49394 | N-Nitroso Fluoxetine | 150494-06-7 | >95.00% | |
A derivative of fluoxetine | ||||
| GC49404 | Paclitaxel C | 153415-45-3 | >95.00% | |
A taxoid and an inhibitor of microtubule depolymerization | ||||
| GC49412 | NSC 756093 | 1629908-92-4 | >98.00% | |
NSC 756093 هو مثبط قوي لتفاعل GBP1: PIM1. يمكن لـ NSC 756093 أن يعيد المقاومة إلى باكليتاكسيل. يمكن استخدام NSC 756093 في أبحاث سرطان المبيض. | ||||
| GC49419 | Aniline-d5 | 4165-61-1 | >99.00% | |
An internal standard for the quantification of aniline | ||||
| GC49430 | Wee1 Inhibitor | 622855-37-2 | >95.00% | |
مثبط Wee1 هو أحد مثبطات Wee1 kinase القوية مع IC50 من 0.011 μ ؛ M. | ||||
| GC49437 | Gliotoxin-13C13 | - | >95.00% | |
An internal standard for the quantification of gliotoxin | ||||
| GC49443 | 7α-hydroxy Cholesterol | 566-26-7 | >98.00% | |
7α-hydroxy Cholesterol هو أكسيد كولسترول ويتكون من الأكسدة الأنزيمية وغير الأنزيمية. | ||||
| GC49460 | ING-2 AM | 1642554-49-1 | >90.00% | |
A cell-permeable fluorescent sodium indicator | ||||
| GC49463 | IPG-2 AM | 1369302-24-8 | >90.00% | |
A cell-permeable fluorescent potassium indicator | ||||
| GC49466 | IPG-2 TMA | 1369302-21-5 | >90.00% | |
A cell-impermeable fluorescent potassium indicator | ||||
| GC49468 | IPG-1 AM | 1369302-18-0 | >90.00% | |
A cell-permeable fluorescent potassium indicator | ||||
| GC49469 | IPG-1 TMA | 1369302-17-9 | >90.00% | |
A cell-impermeable fluorescent potassium indicator | ||||
| GC49471 | LAMP1 Monoclonal Antibody (Clone Ly1C6) | - | - | |
For immunochemical analysis of LAMP1 | ||||
| GC49482 | (±)-Nornicotine-d4 | 66148-18-3 | >99.00% | |
An internal standard for the quantification of (±)-nornicotine | ||||
| GC49486 | Meglutol-d3 | 59060-36-5 | >99.00% | |
An internal standard for the quantification of meglutol | ||||
| GC49491 | N′-Nitrosonornicotine-d4 | 66148-19-4 | >99.00% | |
An internal standard for the quantification of N’-nitrosonornicotine | ||||
| GC49532 | S-(1,2-Dichlorovinyl)-Cysteine (hydrochloride) | 2508026-62-6 | >95.00% | |
A nephrotoxin and metabolite of trichloroethylene | ||||
| GC49547 | L-Glutamic Acid γ-p-Nitroanilide (hydrate) | 122864-94-2 | >95.00% | |
A colorimetric substrate for γ-glutamyl transpeptidase | ||||
| GC49605 | H-Gly-Pro-Hyp-OH (acetate) | 103192-50-3 | >95.00% | |
A peptide DPP-4 inhibitor | ||||
| GC49671 | 2,3-Oxidosqualene | 7200-26-2 | >90.00% | |
An intermediate in the biosynthesis of sterols | ||||
| GC49674 | Schizandrin | 7432-28-2 | >97.00% | |
يتم عزل شيزاندرين (شيزاندرين) ، وهو قشور ثنائي البنزين حلقي حلقي ، من ثمار شيساندرا تشينينسيس بايل. | ||||
| GC49682 | Dabigatran-d3 | 1246817-44-6 | >99.00% | |
An internal standard for the quantification of dabigatran | ||||
| GC49684 | Dabigatran-13C-d3 | 2967480-55-1 | >99.00% | |
An internal standard for the quantification of dabigatran | ||||