Cell Cycle/Checkpoint
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.
Research Areas
- ATM/ATR(28)
- Aurora Kinase(36)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(52)
- CRM1(10)
- Cyclin-Dependent Kinases(70)
- E1 enzyme(1)
- G-quadruplex(16)
- Haspin(7)
- HMTase(1)
- Kinesin(32)
- Ksp(4)
- Microtubule/Tubulin(304)
- Mps1(17)
- Mitotic(7)
- RAD51(13)
- ROCK(76)
- Rho(13)
- PERK(22)
- PLK(51)
- PTEN(7)
- Wee1(17)
- PAK(29)
- Arp2/3 Complex(10)
- Dynamin(18)
- ECM & Adhesion Molecules(53)
- Cholesterol Metabolism(10)
- Endomembrane System & Vesicular Trafficking(34)
- G1(50)
- G2/M(35)
- G2/S(16)
- Genotoxic Stress(22)
- Inositol Phosphates(65)
- Proteolysis(179)
- Cytoskeleton & Motor Proteins(77)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(2)
- MARK(4)
- NEKs(9)
- ATF6(2)
- ClpP(6)
- Disulfidptosis(1)
- HMG Family(1)
- PDI(1)
- SWI/SNF Complex(7)
- VISTA(4)
- HOXA(1)
- Mitosis(1)
Products Related to Cell Cycle/Checkpoint(1551)
- GC49690(3R,5R)-Rosuvastatin (calcium salt)CAS: 1422515-55-6Purity: >95.00%
A potential impurity found in bulk preparations of rosuvastatin
- GC49723SenTraGor™ Cell Senescence ReagentCAS: 2171036-89-6Purity: >95.00%
A cellular senescence detection reagent
- GC4973610-acetyl DocetaxelCAS: 125354-16-7Purity: >98.00%
10-أسيتيل دوسيتاكسيل (10-أسيتيل دوسيتاكسيل) هو نظير لدوسيتاكسيل ، مع نشاط مضاد للسرطان. Docetaxel هو مثبط لتفكيك الأنابيب الدقيقة ، مع نشاط مضاد.
- GC49740Brevetoxin 3CAS: 85079-48-7Purity: >95.00%
Brevetoxin 3 (PbTx-3) عبارة عن منشط قوي لقناة Na+ مبوب بالجهد الخيفي وله عدة مراكز نشطة (A-ring lactone، C-42 of R side chain).
- GC49757Bazedoxifene N-oxideCAS: 1174289-22-5Purity: >90.00%
An oxidative degradation product of bazedoxifene
- GC49771rac-Hesperetin-d3CAS: 1346605-26-2Purity: >99.00%
An internal standard for the quantification of hesperetin
- GC49773Albendazole sulfone-d3CAS: 1448345-60-5Purity: >99.00%
An internal standard for the quantification of albendazole sulfone
- GC49835Tumulosic AcidCAS: 508-24-7Purity: >98.00%
حمض Tumulosic ، ترايتيربينويد ، يثبط نشاط البروتياز KLK5 (IC50 = 14.84 μ ؛ M).
- GC49836BenoxaprofenCAS: 51234-28-7Purity: >98.00%
البينوكسابروفين (LRCL 3794) هو مركب قوي وطويل الأمد مضاد للالتهابات وخافض للحرارة
- GC49855Harmalol (hydrochloride hydrate)CAS: 6028-00-8Purity: >98.00%
A β-carboline alkaloid and an active metabolite of harmaline
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49690 | (3R,5R)-Rosuvastatin (calcium salt) | 1422515-55-6 | >95.00% | |
A potential impurity found in bulk preparations of rosuvastatin | ||||
| GC49695 | FKBP52 Monoclonal Antibody (Clone Hi52C) | - | - | |
For immunochemical analysis of FKBP52 | ||||
| GC49699 | Acetyl Tetrapeptide-9 (acetate) | - | >95.00% | |
A synthetic signal peptide | ||||
| GC49702 | Papain Inhibitor (trifluoroacetate salt) | - | >95.00% | |
A peptide inhibitor of papain | ||||
| GC49704 | Ac-FLTD-CMK (trifluoroacetate salt) | - | >95.00% | |
An inhibitor of caspase-1, -4, -5, and -11 | ||||
| GC49709 | cyclo(RGDyC) (trifluoroacetate salt) | - | >98.00% | |
A cyclic pentapeptide | ||||
| GC49713 | SIKVAV (acetate) | - | >98.00% | |
A laminin α1-derived peptide | ||||
| GC49723 | SenTraGor™ Cell Senescence Reagent | 2171036-89-6 | >95.00% | |
A cellular senescence detection reagent | ||||
| GC49724 | BIO-1211 (trifluoroacetate salt) | - | >98.00% | |
A peptide inhibitor of α4β1 integrin | ||||
| GC49735 | Thallos AM | 1802991-71-4 | >95.00% | |
A cell-permeable fluorescent thallium indicator | ||||
| GC49736 | 10-acetyl Docetaxel | 125354-16-7 | >98.00% | |
10-أسيتيل دوسيتاكسيل (10-أسيتيل دوسيتاكسيل) هو نظير لدوسيتاكسيل ، مع نشاط مضاد للسرطان. Docetaxel هو مثبط لتفكيك الأنابيب الدقيقة ، مع نشاط مضاد. | ||||
| GC49740 | Brevetoxin 3 | 85079-48-7 | >95.00% | |
Brevetoxin 3 (PbTx-3) عبارة عن منشط قوي لقناة Na+ مبوب بالجهد الخيفي وله عدة مراكز نشطة (A-ring lactone، C-42 of R side chain). | ||||
| GC49742 | Hsf1 Monoclonal Antibody (Clone 10H8) | - | - | |
For immunochemical analysis of Hsf1 | ||||
| GC49744 | GRP94 Monoclonal Antibody (Clone 9G10) | - | - | |
For immunochemical detection of GRP94 | ||||
| GC49751 | Lefamulin | 1061337-51-6 | >95.00% | |
ليفامولين (قبل الميلاد -3781) هو مضاد حيوي فعال عن طريق الفم. | ||||
| GC49757 | Bazedoxifene N-oxide | 1174289-22-5 | >90.00% | |
An oxidative degradation product of bazedoxifene | ||||
| GC49771 | rac-Hesperetin-d3 | 1346605-26-2 | >99.00% | |
An internal standard for the quantification of hesperetin | ||||
| GC49773 | Albendazole sulfone-d3 | 1448345-60-5 | >99.00% | |
An internal standard for the quantification of albendazole sulfone | ||||
| GC49781 | Benomyl | 17804-35-2 | >95.00% | |
A carbamate pesticide | ||||
| GC49804 | Acridine | 260-94-6 | >98.00% | |
An azaarene | ||||
| GC49835 | Tumulosic Acid | 508-24-7 | >98.00% | |
حمض Tumulosic ، ترايتيربينويد ، يثبط نشاط البروتياز KLK5 (IC50 = 14.84 μ ؛ M). | ||||
| GC49836 | Benoxaprofen | 51234-28-7 | >98.00% | |
البينوكسابروفين (LRCL 3794) هو مركب قوي وطويل الأمد مضاد للالتهابات وخافض للحرارة | ||||
| GC49855 | Harmalol (hydrochloride hydrate) | 6028-00-8 | >98.00% | |
A β-carboline alkaloid and an active metabolite of harmaline | ||||
| GC49863 | Cytarabine 5′-monophosphate | 7075-11-8 | >95.00% | |
An active metabolite of cytarabine | ||||