Sarcosine |
رقم الكتالوجGC11195 |
Sarcosine (N-Methylglycine) ، وهو حمض أميني داخلي ، هو مثبط تنافسي من النوع الأول (GlyT1) لناقل الجليسين و N-methyl-D-aspartate (NMDA)يزيد الساركوزين من تركيز الجلايسين ، مما يؤدي إلى تقوية غير مباشرة لمستقبل NMDAيشيع استخدام الساركوزين في البحث عن مرض انفصام الشخصية
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Cas No.: 107-97-1
Sample solution is provided at 25 µL, 10mM.
Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site.
References:
[1]. Zhang HX, et al. The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine. J Physiol. 2009 Jul 1;587(Pt 13):3207-20.
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