Sarcosine |
| Katalog-Nr.GC11195 |
Sarcosin (N-Methylglycin), eine endogene AminosÄure, ist ein kompetitiver Inhibitor des Glycin-Transporters Typ I (GlyT1) und ein Co-Agonist des N-Methyl-D-Aspartat (NMDA)-Rezeptors. Sarcosin erhÖht die Glycinkonzentration, was zu einer indirekten Potenzierung des NMDA-Rezeptors fÜhrt. Sarkosin wird hÄufig fÜr die Erforschung von Schizophrenie verwendet.
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Cas No.: 107-97-1
Sample solution is provided at 25 µL, 10mM.
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Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site.
References:
[1]. Zhang HX, et al. The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine. J Physiol. 2009 Jul 1;587(Pt 13):3207-20.
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