Sarcosine |
| Catalog No.GC11195 |
La sarcosina (N-metilglicina), un aminoÁcido endÓgeno, es un inhibidor competitivo del transportador de glicina tipo I (GlyT1) y coagonista del receptor de N-metil-D-aspartato (NMDA). La sarcosina aumenta la concentraciÓn de glicina, lo que da como resultado una potenciaciÓn indirecta del receptor NMDA. La sarcosina se usa comÚnmente para la investigaciÓn de la esquizofrenia.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 107-97-1
Sample solution is provided at 25 µL, 10mM.
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Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site.
References:
[1]. Zhang HX, et al. The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine. J Physiol. 2009 Jul 1;587(Pt 13):3207-20.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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