الصفحة الرئيسية>>Signaling Pathways>> Neuroscience>> Neurokinin Receptor>>Saredutant (SR 48968)

Saredutant (SR 48968) (Synonyms: SR 48968; SR 48968C)

رقم الكتالوجGC31143

Saredutant (SR 48968) هو مضاد انتقائي لمستقبل NK2.

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Saredutant (SR 48968) التركيب الكيميائي

Cas No.: 142001-63-6

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
394٫00
متوفر
1mg
167٫00
متوفر
5mg
324٫00
متوفر
10mg
510٫00
متوفر
25mg
918٫00
متوفر
50mg
1530٫00
متوفر
100mg
2086٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description Protocol Chemical Properties Product Documents Related Products

Saredutant is a selective NK2 receptor antagonist.

Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression. Saredutant has dose-dependent effects on swim test immobility, with the low dose of 1 mg/kg having no effect and the doses of 3 and 10 mg/kg significantly reducing immobility[1].

[1]. Overstreet DH, et al. Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with Desipramine in an animal model of depression. Pharmacol Biochem Behav. 2010 Aug;96(2):206-10.

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