Saredutant (SR 48968) (Synonyms: SR 48968; SR 48968C) |
| Katalog-Nr.GC31143 |
Saredutant (SR 48968) ist ein selektiver NK2-Rezeptorantagonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 142001-63-6
Sample solution is provided at 25 µL, 10mM.
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Saredutant is a selective NK2 receptor antagonist.
Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression. Saredutant has dose-dependent effects on swim test immobility, with the low dose of 1 mg/kg having no effect and the doses of 3 and 10 mg/kg significantly reducing immobility[1].
[1]. Overstreet DH, et al. Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with Desipramine in an animal model of depression. Pharmacol Biochem Behav. 2010 Aug;96(2):206-10.
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