SJF 8240 |
| رقم الكتالوجGC50753 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2230821-68-6
Sample solution is provided at 25 µL, 10mM.
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c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089; ) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells.
Review for SJF 8240
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
Review for SJF 8240
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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