STAT5-IN-2 |
| رقم الكتالوجGC65344 |
STAT5-IN-2 هو مثبط STAT5 ، مستخرج من المرجع 1 ، المثال 17fSTAT5-IN-2 له تأثير قوي مضاد للوكيميا
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2111834-61-6
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
STAT5-IN-2 is a STAT5 inhibitor, extracted from reference 1, example 17f. STAT5-IN-2 has potent antileukemic effect[1].
STAT5-IN-2 has EC50 values of 9 μM and 5 μM in K562 and KU812 cells, respectively[1].STAT5-IN-2 (100 nM-50 µM; 48 hours) has EC50 values of 2.6 µM and 3.5 µM in KG1a and MV-4-11 cells, respectively[1].STAT5-IN-2 (10 µM; 48 hours) induces apoptosis in all cell lines (K562, KU812, KG1a and MV-4-11 cells)[1]. STAT5-IN-2 (10 µM; 24 hours) blocks phosphorylation of STAT5[1].
[1]. Ludovic Juen, et al. New Inhibitor Targeting Signal Transducer and Activator of Transcription 5 (STAT5) Signaling in Myeloid Leukemias. J Med Chem. 2017 Jul 27;60(14):6119-6136.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *