Taurohyodeoxycholic Acid |
| رقم الكتالوجGC41562 |
حمض Taurohyodeoxycholic هو الشكل المقترن من حمض هيوديوكسيكوليك (HDCA ، حمض الصفراء الطبيعي ثنائي هيدروكسيل)
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Cas No.: 2958/4/5
Sample solution is provided at 25 µL, 10mM.
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Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.
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