DNA Damage/DNA Repair
Research Areas
- MTH1(4)
- PARP(103)
- ATM/ATR(31)
- DNA Alkylating(23)
- DNA Ligases(3)
- DNA Methyltransferase(27)
- DNA-PK(28)
- HDAC(143)
- Nucleoside Antimetabolite/Analogue(194)
- Telomerase(15)
- Topoisomerase(193)
- tankyrase(5)
- Antifolate(33)
- CDK(299)
- Checkpoint Kinase (Chk)(36)
- CRISPR/Cas9(9)
- Deubiquitinase(84)
- DNA Alkylator/Crosslinker(87)
- DNA/RNA Synthesis(575)
- Eukaryotic Initiation Factor (eIF)(33)
- IRE1(25)
- LIM Kinase (LIMK)(12)
- TOPK(6)
- Casein Kinase(59)
- DNA Intercalating Agents(8)
- DNA/RNA Oxidative Damage(13)
- Poly(ADP-ribose) Glycohydrolase (PARG)(5)
- Early 2 Factor (E2F)(2)
- Zinc Finger Protein(1)
Products Related to DNA Damage/DNA Repair(1968)
- GC81398m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG tetraammonium solution (100 mM)Purity: >99.00%
m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG tetraammonium solution (100 mM) is a cap analog that can be used for in vitro transcription of mRNA.
- GC81399m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium solution (100 mM)Purity: >98.50%
m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium, a cap analogue derived from patent WO2023159930A1, can be used for the synthesis of mRNA [1] .
- GC81413Biotin-7-GMP lithium solution (100 mM ± 3 mM)Purity: >99.50%
Biotin-7-GMP (5'-Biotin-G-monophosphate) lithium solution (100 mM ± 3 mM) is a 5'-biotinylated guanosine monophosphate reagent.
- GC81465Methacrylate C6 phosphoramiditeCAS: 1226983-36-3Purity: >98%
Methacrylate C6 phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
- GC81466DMT-PEG4 PhosphoramiditeCAS: 158041-83-9Purity: >98.00%
DMT-PEG4 Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
- GC81469Morpholino-G(N-iBu) PhosphoramiditeCAS: 956139-25-6Purity: >98%
Morpholino-G(N-iBu) Phosphoramidite is a guanine-containing morpholino phosphoramidite building block with an isobutyryl (iBu)-protected guanine amino group.
- GC81470DMT-NH-PEG4-phosphoramiditeCAS: 3099406-90-0Purity: >98.00%
1,1-Bis(4-methoxyphenyl)-1-phenyl-3,6,9,12-tetraoxa-2-azatetradecan-14-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
- GC81471β-L-dT-CE phosphoramiditeCAS: 141846-55-1Purity: >98%
β-L-dT-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
- GC81472pdU-CE PhosphoramiditeCAS: 198080-43-2Purity: >98%
pdU-CE Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
- GC81473Amino-modifier-C6-dC CEPCAS: 853955-92-7Purity: >98%
(2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-2-oxo-5-(3-oxo-3-((6-(2,2,2-trifluoroacetamido)hexyl)amino)prop-1-en-1-yl)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
- GC814744'-O-CH2-phosphate methyl ester-2'-O-Me-rU-3'-CE-phosphoramiditeCAS: 2197181-94-3Purity: >98%
4'-O-CH2-phosphate methyl ester-2'-O-Me-rU-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
- GC81475Thiol-modifier C6 S-S CE phosphoramiditeCAS: 148254-21-1Purity: >98.00%
Thiol-modifier C6 S-S CE phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
- GC81476DMTr-2'-O-Propargyl-rU-3'-CE-phosphoramiditeCAS: 171486-62-7Purity: >98%
DMTr-2'-O-propargyl-rU-3'-CE -Phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
- GC81477DMTr-2'-O-C16-rU-3'-CE-phosphoramiditeCAS: 2382942-83-6Purity: >98.00%
DMTr-2'-O-C16-rU-3'-CE-Phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
- GC81478DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-phosphoramiditeCAS: 2379296-27-0Purity: >98%
DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
- GC81500Ac-rG Phosporamidite- 15 NCAS: 1799973-39-9Purity: >98%
Ac-rG Phosporamidite - 15 N (5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite- 15 N) is the 15 N-labeled Ac-rG Phosporamidite.
- GC81501Ac-rG Phosporamidite- 13 CPurity: >98%
Ac-rG Phosporamidite - 13 C (5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite- 13 C) is the 13 C-labeled Ac-rG Phosporamidite.
- GC81502Ac-rG Phosporamidite- 13 C 10Purity: >98%
Ac-rG Phosporamidite - 13 C 10 (5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite- 13 C 10 ) is the 13 C-labeled Ac-rG Phosporamidite.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81398 | m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG tetraammonium solution (100 mM) | - | >99.00% | |
m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG tetraammonium solution (100 mM) is a cap analog that can be used for in vitro transcription of mRNA. | ||||
| GC81399 | m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium solution (100 mM) | - | >98.50% | |
m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium, a cap analogue derived from patent WO2023159930A1, can be used for the synthesis of mRNA [1] . | ||||
| GC81413 | Biotin-7-GMP lithium solution (100 mM ± 3 mM) | - | >99.50% | |
Biotin-7-GMP (5'-Biotin-G-monophosphate) lithium solution (100 mM ± 3 mM) is a 5'-biotinylated guanosine monophosphate reagent. | ||||
| GC81448 | Indaziflam | 950782-86-2 | >99.50% | |
Indaziflam is an alkyltriazine herbicide. | ||||
| GC81453 | FOXM1-IN-3 | - | >98% | |
FOXM1-IN-3 is a potent FOXM1 inhibitor. | ||||
| GC81461 | FPP29 | - | >99.00% | |
FPP29 is a potent peptide-based FOXM1 PROTAC degrader. | ||||
| GC81465 | Methacrylate C6 phosphoramidite | 1226983-36-3 | >98% | |
Methacrylate C6 phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides. | ||||
| GC81466 | DMT-PEG4 Phosphoramidite | 158041-83-9 | >98.00% | |
DMT-PEG4 Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides. | ||||
| GC81468 | MS102 | 3058587-77-9 | >98% | |
MS102 is an orally active ubiquitin specific peptidase 2 ( USP2 ) inhibitor with an IC 50 of 5.46 μM. | ||||
| GC81469 | Morpholino-G(N-iBu) Phosphoramidite | 956139-25-6 | >98% | |
Morpholino-G(N-iBu) Phosphoramidite is a guanine-containing morpholino phosphoramidite building block with an isobutyryl (iBu)-protected guanine amino group. | ||||
| GC81470 | DMT-NH-PEG4-phosphoramidite | 3099406-90-0 | >98.00% | |
1,1-Bis(4-methoxyphenyl)-1-phenyl-3,6,9,12-tetraoxa-2-azatetradecan-14-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides. | ||||
| GC81471 | β-L-dT-CE phosphoramidite | 141846-55-1 | >98% | |
β-L-dT-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides. | ||||
| GC81472 | pdU-CE Phosphoramidite | 198080-43-2 | >98% | |
pdU-CE Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides. | ||||
| GC81473 | Amino-modifier-C6-dC CEP | 853955-92-7 | >98% | |
(2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-2-oxo-5-(3-oxo-3-((6-(2,2,2-trifluoroacetamido)hexyl)amino)prop-1-en-1-yl)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides. | ||||
| GC81474 | 4'-O-CH2-phosphate methyl ester-2'-O-Me-rU-3'-CE-phosphoramidite | 2197181-94-3 | >98% | |
4'-O-CH2-phosphate methyl ester-2'-O-Me-rU-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC81475 | Thiol-modifier C6 S-S CE phosphoramidite | 148254-21-1 | >98.00% | |
Thiol-modifier C6 S-S CE phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC81476 | DMTr-2'-O-Propargyl-rU-3'-CE-phosphoramidite | 171486-62-7 | >98% | |
DMTr-2'-O-propargyl-rU-3'-CE -Phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC81477 | DMTr-2'-O-C16-rU-3'-CE-phosphoramidite | 2382942-83-6 | >98.00% | |
DMTr-2'-O-C16-rU-3'-CE-Phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC81478 | DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-phosphoramidite | 2379296-27-0 | >98% | |
DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC81481 | SKLB06489 | - | >98% | |
SKLB06489 is a selective and orally active inhibitor of type I PRMT enzymes, with IC 50 values of 64.55 nM ( PRMT1 ), 4.21 nM ( PRMT6 ), and 51.27 nM ( PRMT8 ). | ||||
| GC81499 | CT-179 | 1996636-69-1 | >99.50% | |
CT-179 is a brain-penetrant and orally active OLIG2 inhibitor with a human IC 50 of 1250 nM. | ||||
| GC81500 | Ac-rG Phosporamidite- 15 N | 1799973-39-9 | >98% | |
Ac-rG Phosporamidite - 15 N (5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite- 15 N) is the 15 N-labeled Ac-rG Phosporamidite. | ||||
| GC81501 | Ac-rG Phosporamidite- 13 C | - | >98% | |
Ac-rG Phosporamidite - 13 C (5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite- 13 C) is the 13 C-labeled Ac-rG Phosporamidite. | ||||
| GC81502 | Ac-rG Phosporamidite- 13 C 10 | - | >98% | |
Ac-rG Phosporamidite - 13 C 10 (5'-DMT-2'-TBDMS-rG(N-Ac) Phosphoramidite- 13 C 10 ) is the 13 C-labeled Ac-rG Phosporamidite. | ||||