GLPBio

DNA Damage/DNA Repair

Research Areas

Products Related to DNA Damage/DNA Repair(2120)

  • GC81308 structure
    GC81308DYRK2-IN-2 hydrochloride
    Purity: >98.00%

    DYRK2-IN-2 hydrochloride is a selective DYRK2 inhibitor with an IC 50 of 40.3 nM.

  • GC81309 structure
    GC81309AO-365/43472821
    CAS: 1081122-55-5
    Purity: >99.50%

    AO-365/43472821 is a selective, brain-penetrant Dual-specificity tyrosine phosphorylation-regulated kinase 1A ( DYRK1A ) inhibitor ( IC 50 = 0.29 μM) and shows a significant inhibitory effect on ( CDC-like kinase 1) CLK1 ( IC 50 = 0.08 μM).

  • GC81312 structure
    GC81312PARP1/c-Met-IN-3
    CAS: 3123529-62-1
    Purity: >98.00%

    PARP1/c-Met-IN-3 (Compound L19) is a selective c-Met and PARP1 inhibitor, with an IC 50 of 5.4 nM against c-Met and an IC 50 of 3.7 nM against PARP1.

  • GC81336 structure
    GC81336KY19334
    CAS: 2319609-67-9
    Purity: >99.50%

    KY19334 is a CXXC5-DVL inhibitor.

  • GC81394 structure
    GC81394PPA-037 TFA
    Purity: >99.00%

    PPA-037 TFA is an orally active, highly potent and selective inhibitor of cyclin-dependent kinase 12 ( CDK12 ).

  • GC81395 structure
    GC81395ddhCTP trisodium solution (100 mM ± 3 mM)
    Purity: >98.00%

    ddhCTP trisodium solution (100 mM ± 3 mM) is an endogenously produced pyrimidine base analog with a K d of 17.0 nM for LLDH and an IC 50 of 55.8 μM for GAPDH.

  • GC81396 structure
    GC81396ARCA triammonium solution (100 mM)
    Purity: >98.00%

    ARCA (triammonium) solution (100 mM) (Anti-Reverse cap analog triammonium solution (100 mM); m 2 7,3'O Gppp triammonium solution (100 mM)) is a 5′-cap analog.

  • GC81397 structure
    GC813977-Methyl-diguanosine triphosphate ammonium solution (100 mM)
    CAS: 75252-12-9
    Purity: >98.50%

    7-Methyl-diguanosine triphosphate (m7Gp3G) ammonium is an mRNA cap structure analog that inhibits in vitro protein synthesis by binding to the translation initiation complex.

  • GC81398 structure
    GC81398m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG tetraammonium solution (100 mM)
    Purity: >99.00%

    m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG tetraammonium solution (100 mM) is a cap analog that can be used for in vitro transcription of mRNA.

  • GC81399 structure
    GC81399m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium solution (100 mM)
    Purity: >98.50%

    m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium, a cap analogue derived from patent WO2023159930A1, can be used for the synthesis of mRNA [1] .

  • GC81413 structure
    GC81413Biotin-7-GMP lithium solution (100 mM ± 3 mM)
    Purity: >99.50%

    Biotin-7-GMP (5'-Biotin-G-monophosphate) lithium solution (100 mM ± 3 mM) is a 5'-biotinylated guanosine monophosphate reagent.

  • GC81448 structure
    GC81448Indaziflam
    CAS: 950782-86-2
    Purity: >99.50%

    Indaziflam is an alkyltriazine herbicide.

  • GC81453 structure
    GC81453FOXM1-IN-3
    Purity: >98.00%

    FOXM1-IN-3 is a potent FOXM1 inhibitor.

  • GC81461 structure
    GC81461FPP29
    Purity: >99.00%

    FPP29 is a potent peptide-based FOXM1 PROTAC degrader.

  • GC81465 structure
    GC81465Methacrylate C6 phosphoramidite
    CAS: 1226983-36-3
    Purity: >98.00%

    Methacrylate C6 phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

  • GC81466 structure
    GC81466DMT-PEG4 Phosphoramidite
    CAS: 158041-83-9
    Purity: >98.00%

    DMT-PEG4 Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

  • GC81468 structure
    GC81468MS102
    CAS: 3058587-77-9
    Purity: >98.00%

    MS102 is an orally active ubiquitin specific peptidase 2 ( USP2 ) inhibitor with an IC 50 of 5.46 μM.

  • GC81469 structure
    GC81469Morpholino-G(N-iBu) Phosphoramidite
    CAS: 956139-25-6
    Purity: >98.00%

    Morpholino-G(N-iBu) Phosphoramidite is a guanine-containing morpholino phosphoramidite building block with an isobutyryl (iBu)-protected guanine amino group.

  • GC81470 structure
    GC81470DMT-NH-PEG4-phosphoramidite
    CAS: 3099406-90-0
    Purity: >98.00%

    1,1-Bis(4-methoxyphenyl)-1-phenyl-3,6,9,12-tetraoxa-2-azatetradecan-14-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

  • GC81471 structure
    GC81471β-L-dT-CE phosphoramidite
    CAS: 141846-55-1
    Purity: >98.00%

    β-L-dT-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

  • GC81472 structure
    GC81472pdU-CE Phosphoramidite
    CAS: 198080-43-2
    Purity: >98.00%

    pdU-CE Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

  • GC81473 structure
    GC81473Amino-modifier-C6-dC CEP
    CAS: 853955-92-7
    Purity: >98.00%

    (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-2-oxo-5-(3-oxo-3-((6-(2,2,2-trifluoroacetamido)hexyl)amino)prop-1-en-1-yl)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

  • GC81474 structure
    GC814744'-O-CH2-phosphate methyl ester-2'-O-Me-rU-3'-CE-phosphoramidite
    CAS: 2197181-94-3
    Purity: >98.00%

    4'-O-CH2-phosphate methyl ester-2'-O-Me-rU-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.

  • GC81475 structure
    GC81475Thiol-modifier C6 S-S CE phosphoramidite
    CAS: 148254-21-1
    Purity: >98.00%

    Thiol-modifier C6 S-S CE phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.