Ac-FEID-CMK TFA |
| Catalog No.GC65107 |
Ac-FEID-CMK TFA es un potente inhibidor peptÍdico derivado de GSDMEb especÍfico del pez cebra.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Ac-FEID-CMK TFA is a potent zebrafish-specific GSDMEb-derived peptide inhibitor. Ac-FEID-CMK TFA can attenuate the mortality and kidney injury during septic shock. Ac-FEID-CMK TFA inhibits pyroptosis and attenuates septic AKI (acute kidney injury) in vivo. Ac-FEID-CMK TFA can suppress the caspy2-mediated noncanonical inflammasome pathway[1].
[1]. Wang Z, et al. Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo. J Immunol. 2020 Apr 1;204(7):1929-1942.
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