Ac-FEID-CMK TFA |
| Katalog-Nr.GC65107 |
Ac-FEID-CMK TFA ist ein potenter Zebrafisch-spezifischer, von GSDMEb abgeleiteter Peptid-Inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Ac-FEID-CMK TFA is a potent zebrafish-specific GSDMEb-derived peptide inhibitor. Ac-FEID-CMK TFA can attenuate the mortality and kidney injury during septic shock. Ac-FEID-CMK TFA inhibits pyroptosis and attenuates septic AKI (acute kidney injury) in vivo. Ac-FEID-CMK TFA can suppress the caspy2-mediated noncanonical inflammasome pathway[1].
[1]. Wang Z, et al. Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo. J Immunol. 2020 Apr 1;204(7):1929-1942.
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