ADAMTS-5 Inhibitor |
| Catalog No.GC42722 |
ADAMTS-5 Inhibitor es un potente inhibidor de ADAMTS-5 (agrecanasa-2), con una IC50 de 1,1 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 929634-33-3
Sample solution is provided at 25 µL, 10mM.
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A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage. While it has key roles in cartilage destruction associated with osteoarthritis, ADAMTS-5 is also involved in other pathways, including neurological processes. ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 (aggrecanase-2; IC50 = 1.1 µM) with 40-fold selectivity over ADAMTS-4 (aggrecanase-1).
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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